Long-acting ß-agonists may make asthma worse. A study in Annals of Internal Medicine analyzed date from 19 clinical trials involving 33, 826 patients. Those using the drugs were twice as likely to have life-threatening asthma attacks as patients on a placebo and 2.5 times as likely to be hospitalized. LABAs may also be responsible for thousands of asthma deaths each year in the United States, according to this study.
Source: Online Annals of Internal Medicine June 20, 2006 Volume 144 Issue 12
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